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Induction Tx for healthy 79 yo pt, high risk, normal renal function?Induction Tx for healthy 79 yo pt, high risk, normal renal function?What is your preferred induction treatment for an otherwise healthy 79-year-old patient with high-risk MM and normal renal function who is not eligible for transplant?
Benboubker L et al. FIRST Trial Team. Lenalidomide and dexamethasone in transplant-ineligible patients with myeloma. N Engl J Med 2014;371(10):906-17. Abstract Cejalvo MJ, de la Rubia J. Front-line lenalidomide therapy in patients with newly diagnosed multiple myeloma. Future Oncol 2015;11(11):1643-58. Abstract Mateos MV, San Miguel JF. How should we treat newly diagnosed multiple myeloma patients? Hematology Am Soc Hematol Educ Program 2013;488-95. Abstract Mateos MV et al. Bortezomib plus melphalan and prednisone compared with melphalan and prednisone in previously untreated multiple myeloma: Updated follow-up and impact of subsequent therapy in the phase III VISTA trial. J Clin Oncol 2010;28(13):2259-66. Abstract Paszekova H et al. High-risk multiple myeloma: Different definitions, different outcomes? Clin Lymphoma Myeloma Leuk 2014;14(1):24-30. Abstract Rajkumar V. Multiple myeloma: 2014 Update on diagnosis, risk-stratification, and management. Am J Hematol 2014;89(10):999-1009. Abstract |