Target Audience
This program is intended for medical oncologists, hematologists, hematology-oncology fellows and other allied healthcare professionals involved in the treatment of immune thrombocytopenia.
Learning Objectives
Upon completion of this activity, participants should be able to
- Evaluate factors, including age, comorbidities, bleeding history/risk, lifestyle and personal preferences, that influence the decision to initiate active therapy for immune thrombocytopenia (ITP), and counsel patients regarding personalized initial treatment recommendations.
- Appraise available guidelines concerning the recommended duration of corticosteroid use as initial therapy for ITP, and identify patients who experience insufficient response or relapse after steroids for whom a change of treatment may be warranted.
- Understand available efficacy and safety data with FDA-approved second- and later-line treatments for ITP, and consider this information in the selection and sequencing of therapy for patients with persistent/chronic disease.
- Recollect available research with novel agents and strategies, including those targeting the B-cell activating factor receptor, under investigation for ITP in preparation for their potential clinical availability.
- Discern the side effects and toxicities associated with available and investigational therapies used in the care of patients with ITP, and identify strategies to manage and mitigate them.
CE Credit
CME and ABIM MOC credit information will be provided to each participant at the conclusion of the activity.
Accreditation Statement
Research To Practice is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Credit Designation Statement
Research To Practice designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
American Board of Internal Medicine (ABIM) — Maintenance of Certification (MOC)
Successful completion of this CME activity, which includes participation in the evaluation component and a post-test, enables the participant to earn up to 1.5 Medical Knowledge MOC point in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for this activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
Please note, this program has been specifically designed for the following ABIM specialties: medical oncology and hematology.
Privacy Policy
Personal information and data sharing: Research To Practice aggregates deidentified user data for program-use analysis, program development, activity planning and site improvement. We may provide aggregate and deidentified data to third parties, including commercial supporters. We do not share or sell personally identifiable information to any unaffiliated third parties or commercial supporters. Please see our privacy policy at ResearchToPractice.com/Privacy-Policy for more information.
Unlabeled/Unapproved Uses Notice
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the Food and Drug Administration. Research To Practice does not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. The opinions expressed are those of the presenters and are not to be construed as those of the provider or grantor.
Content Validation and Disclosures
Research To Practice (RTP) is committed to providing its participants with high-quality, unbiased and state-of-the-art education and adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of an accredited continuing education activity, including faculty, planners, reviewers and others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest will have been mitigated prior to the commencement of this activity. In addition, all activity content is reviewed by RTP scientific staff and an external, independent physician reviewer for fair balance, scientific objectivity of studies referenced and patient care recommendations.
FACULTY — The following faculty reported relevant financial relationships with ineligible entities:
Dr Al-Samkari —
Consulting Agreements: Agios Pharmaceuticals Inc, Alnylam, Alpine Immune Sciences, Amgen Inc, Novartis, Pharmacosmos, Sanofi, Sobi, Takeda Pharmaceuticals USA Inc;
Contracted Research: Agios Pharmaceuticals Inc, Amgen Inc, Novartis, Sobi, Vaderis Therapeutics AG.
Dr Neunert —
Advisory Committees: Novartis, Sanofi;
Consulting Agreements: Janssen Biotech Inc;
Contracted Research: Novartis;
Data and Safety Monitoring Boards/Committees: Takeda Pharmaceuticals USA Inc.
Professor Zaja —
Advisory Committees: AbbVie Inc, Amgen Inc, argenx, AstraZeneca Pharmaceuticals LP, BeOne, Gilead Sciences Inc, Grifols, Incyte Corporation, Novartis, Sanofi, Takeda Pharmaceuticals USA Inc;
Consulting Agreements: Amgen Inc, Grifols, Novartis;
Contracted Research: Janssen Biotech Inc;
Speakers Bureaus: AbbVie Inc, Amgen Inc, argenx, AstraZeneca Pharmaceuticals LP, Grifols, Novartis;
Nonrelevant Financial Relationships (Educational Projects on Lymphomas and ITP): AbbVie Inc, Amgen Inc, AstraZeneca Pharmaceuticals LP, BeOne, Grifols, Incyte Corporation, Kyowa Kirin Co Ltd, Sobi.
MODERATOR —
Dr Love is president and CEO of Research To Practice. Research To Practice receives funds in the form of educational grants to develop CME activities from the following companies: Aadi Bioscience, AbbVie Inc, ADC Therapeutics, Agendia Inc, Alexion Pharmaceuticals, Amgen Inc, Array BioPharma Inc, a subsidiary of Pfizer Inc, Arvinas, Astellas, AstraZeneca Pharmaceuticals LP, Aveo Pharmaceuticals, Bayer HealthCare Pharmaceuticals, BeOne, Biotheranostics Inc, A Hologic Company, Black Diamond Therapeutics Inc, Blueprint Medicines, Boehringer Ingelheim Pharmaceuticals Inc, Bristol Myers Squibb, Celcuity, Clovis Oncology, Coherus BioSciences, Corcept Therapeutics Inc, CTI BioPharma, a Sobi Company, Daiichi Sankyo Inc, Eisai Inc, Elevation Oncology Inc, Exact Sciences Corporation, Exelixis Inc, Genentech, a member of the Roche Group, Genmab US Inc, Geron Corporation, Gilead Sciences Inc, GSK, Helsinn Therapeutics (US) Inc, ImmunoGen Inc, Incyte Corporation, Ipsen Biopharmaceuticals Inc, Jazz Pharmaceuticals Inc, Johnson & Johnson, Karyopharm Therapeutics, Kite, A Gilead Company, Kura Oncology, Legend Biotech, Lilly, MEI Pharma Inc, Merck, Mersana Therapeutics Inc, Mirati Therapeutics Inc, Mural Oncology Inc, Natera Inc, Novartis, Novartis Pharmaceuticals Corporation on behalf of Advanced Accelerator Applications, Novocure Inc, Nuvalent, Pfizer Inc, Pharmacyclics LLC, an AbbVie Company, Puma Biotechnology Inc, Regeneron Pharmaceuticals Inc, Rigel Pharmaceuticals Inc, R-Pharm US, Sanofi, Seagen Inc, Servier Pharmaceuticals LLC, SpringWorks Therapeutics Inc, Stemline Therapeutics Inc, Sumitomo Pharma America, Syndax Pharmaceuticals, Taiho Oncology Inc, Takeda Pharmaceuticals USA Inc, TerSera Therapeutics LLC, and Tesaro, A GSK Company.
RESEARCH TO PRACTICE CME PLANNING COMMITTEE MEMBERS, STAFF AND REVIEWERS
Planners, scientific staff and independent reviewers for Research To Practice have no relevant conflicts of interest to disclose.
Supporters
This activity is supported by an educational grant from Novartis.
