Consensus or Controversy: Clinical Investigators Provide Perspectives on Targeted Treatment of Non-Small Cell Lung Cancer | Research To Practice

Consensus or Controversy: Clinical Investigators Provide Perspectives on Targeted Treatment of Non-Small Cell Lung Cancer

Consensus or Controversy: Clinical Investigators Provide Perspectives on Targeted Treatment of Non-Small Cell Lung Cancer

Introduction

1:44 minutes.

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Type of mutation testing prior to first-line treatment?

Clinical Algorithms for Biomarker Testing

Management of Patients with EGFR Tumor Mutations

First-line treatment recommendation for a patient with metastatic NSCLC and EGFR mutation?
Evaluate for T790M mutation after progression on EGFR TKI? Plasma or tissue biopsy? Urine assay?
Therapy recommendation for patient with T790M mutation after progression on erlotinib?
Therapy recommendation for patient who is T790M mutation-negative after progression on erlotinib?
Sequence immune checkpoint inhibitors in patients with tumor mutations?

Management of Patients with ALK and ROS1 Alterations

Identification of Other Potentially Targetable Tumor Mutations