GIinteractive11 | Case 11 - Hepatocellular Cancer


An 80-year-old man in previously good health presents with abdominal pain and is found on CAT scan to have an 8-cm centrally located hepatic mass that on biopsy is HCC. He is also found to have an expansile lytic lesion in the L3 vertebra that is positive on bone scan.

In general, what initial dose of sorafenib do you use for an 80-year-old patient without significant comorbidity?

What is your most likely initial treatment?