MM Working Group | Home


In April, RTP convened a Working Group of multiple myeloma (MM) clinical investigators, practicing hematologists/oncologists and oncology nurse practitioners (click here to see full faculty) to better elucidate current practice patterns in the management of this disease. The event featured a mix of didactic lectures, moderated, case-based discussions and extensive, real-time polling of the group intended to capture the preferred treatment strategies for a number of clinical scenarios.

The eight topic modules below — introduced sequentially via weekly emails over the next two months — provide access to the recorded discussions and conclusions that emerged from the event and are presented in the following formats:

  • Treatment Preference Matrix — Graphical summary of the investigators' preferred
    management approaches for four distinct clinical scenarios, including text-based
    commentary from select investigators.
  • Video Clip from MM Working Group — Short video segment featuring moderated panel discussion related to the topic module.
  • Video Presentations — Mini-lecture with slides by invited clinical investigators related to the topics discussed.
 
Workup, Risk Stratification and Pretransplant Induction Therapy
  • Nikhil C Munshi, MD — Workup and Risk Stratification
  • Sagar Lonial, MD — Risk Assessment in the Relapse Setting
  • Guido Tricot, MD, PhD — Induction Treatment for Younger Transplant-Ineligible Patients
 
Management of Side Effects and Toxicities of Systemic Treatment
  • Ivan Borrello, MD — Bortezomib-Associated Neuropathy
  • Jeffrey A Zonder, MD — Systemic Agents' Toxicities/Side Effects
 
Bone-Targeted Treatment
  • Melissa Alsina, MD — Bone-Targeted Treatment
  • Cristina Gasparetto, MD — Scheduling of Bone-Targeted Agents
  • David S Siegel, MD, PhD — Vertebroplasty and XRT
 
Special Cases
  • Video Clips from MM Working Group
    Faculty presentations and discussions of 7 patient cases:
    •  70 yo man with amyloidosis and macroglossia
    •  95 yo woman with CHF and MM
    •  80 yo woman with plasma cell leukemia
    •  47 yo woman with MGUS
    •  65 yo woman with MGUS
    •  47 yo woman with smoldering myeloma
    •  67 yo man with nonsecretory myeloma

  • Video Presentation
  • Carol Ann Huff, MD — Nutritional Support and Palliative Care
 
Method of Transplant and Post-Transplant Maintenance
  • Ravi Vij, MD — Post-Transplant Maintenance Therapy
  • William I Bensinger, MD — Delayed Transplantation
  • Edward A Stadtmauer, MD — Allo- and Tandem Transplantation
 
New Agents in Development
  • Rafael Fonseca, MD — New Agents in Development
  • Kenneth C Anderson, MD — Access to Trials in the Community Setting
 
Induction Treatment and Maintenance Therapy for Patients Not Eligible for Transplant
  • Antonio Palumbo, MD — Induction Therapy for Older Patients
  • A Keith Stewart, MBChB — Postinduction Maintenance
  • Morie A Gertz, MD — 60-80 yo with Adverse Cytogenetics
  • Jeffrey L Wolf, MD — 60-80 yo with Normal Cytogenetics
 
Management of Patients with Renal Failure
  • Ruben Niesvizky, MD — Induction Older Pts w/ Comorbidities