Oncology Grand Rounds Series: Part 2 — Gastrointestinal Cancers (Webinar Audio Proceedings)



Topic 1: Introduction
Topic 2: Results of the Phase III IMbrave150 trial evaluating atezolizumab/bevacizumab for front-line unresectable hepatocellular carcinoma (HCC); benefits and risks in comparison to multikinase inhibitors
Topic 3: Selection of first-line therapy for patients with advanced HCC; optimal timing of systemic treatment
Topic 4: Efficacy and tolerability data from the Phase III IMbrave150 trial comparing atezolizumab/bevacizumab to sorafenib for front-line advanced HCC
Topic 5: Significance of tumor location and biomarker profile in treatment decision-making for patients with metastatic colorectal cancer (mCRC); use of encorafenib/cetuximab for mCRC with BRAF mutation
Topic 6: Safety and tolerability of regorafenib and TAS-102, each alone or in combination with bevacizumab, for patients with recurrent advanced CRC
Topic 7: Optimal integration of immune checkpoint inhibitors into the therapeutic algorithm for patients with microsatellite instability-high/mismatch repair-deficient mCRC; emerging data with pembrolizumab versus chemotherapy in the up-front setting
Topic 8: Management of side effects from TAS-102; optimal sequencing of TAS-102 and regorafenib for recurrent mCRC
Topic 9: PD-L1 expression and immune checkpoint inhibitor therapy for metastatic gastroesophageal cancer
Topic 10: FDA approval of TAS-102 for patients with heavily pretreated metastatic gastric cancer; appropriate use in clinical care
Topic 11: Impact of COVID-19 on the clinical care of patients with gastrointestinal cancers
Melony Avella-Howell, NP
Aurora, Colorado
Wells A Messersmith, MD
Professor and Head, Division of Medical Oncology
Associate Director for Translational Research
University of Colorado Cancer Center
Aurora, Colorado
Philip A Philip, MD, PhD, FRCP
Kathryn Cramer Endowed Chair in Cancer Research
Professor of Oncology and Pharmacology
Leader, GI and Neuroendocrine Oncology
Karmanos Cancer Institute
Wayne State University
Detroit, Michigan
Tammy Triglianos, RN, MS, ANP-BC, AOCNP
GI Oncology Nurse Practitioner
Lineberger Comprehensive Cancer Center
The University of North Carolina Division of Oncology
Department of Medicine, University of North Carolina
Chapel Hill, North Carolina
Neil Love, MD
Research To Practice
Miami, Florida